Research group of Prof. dr. A.K.H. Hirsch
Since April 2017, Prof. dr. Hirsch has been appointed professor in Medicinal Chemistry at the University of Saarland, Saarbrücken (Germany). Most of the group members, are now working at the Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS).
The research interests of the group are:
1. Structure-based design and synthesis of novel inhibitors
2. Solubilisation of small molecules using selective bioconjugates
3. Dynamic combinatorial chemistry to facilitate drug discovery
Schematic representation of the fundamental concept of protein-templated DCC.