Curriculum Vitae Prof. Dr. A.J. Minnaard

Dr. Adriaan J. MinnaardProf. Dr. Adriaan J. Minnaard

Head of the department of Chemical Biology
Stratingh Institute for Chemistry
Nijenborgh 7, 9747 AG Groningen
University of Groningen, The Netherlands
A.J.Minnaard@rug.nl

Director of the Stratingh Institute for Chemistry

Master degree

University: “Molecular Sciences” at the Agricultural University Wageningen, The Netherlands

Doctorate

University: Agricultural University Wageningen, The Netherlands
Date (dd/mm/yy): 1997 (cum laude)
Supervisor (‘Promotor’): Prof. Dr. Ae. de Groot
Co-promotor: Dr. J.B.P.A. Wijnberg
Title of thesis: Germacrane Sesquiterpenes; Synthesis and Role in Biosynthesis

Career since graduation

1997 – 1999 Researcher at DSM-Research in Geleen.
1999 _ 2005 Assistant Professor at the Stratingh Institute for Chemistry, University of Groningen, in the department of Synthetic Organic Chemistry headed by Prof. Dr. B.L. Feringa
2006 –2009 Associate Professor in Bio-Organic Chemistry, Stratingh Institute for Chemistry.
2006 – 2007 Guest Professor at the Max Planck Institute for Molecular Physiology, Dortmund, Germany, in the Chemical Biology group of Prof. Dr. H. Waldmann.
2007 – Head of the department of Bio-organic Chemistry, Stratingh institute for Chemistry.
2009 – Full Professor in Bio-organic Chemistry, head of the department of Chemical Biology
2016 – Director of the Stratingh Institute for Chemistry

National and international outreach

1987 Member of the Royal Dutch Chemical Society
1991 Master degree Cum Laude (with Honors)
1992 Ph.D. Scholarship at Wageningen Agricultural University
1997 Ph.D. degree Cum Laude (with Honors)
1999 Member of the American Chemical Society
2000 Member of the Dutch Science Foundation Study groups Design and Synthesis, Coordination Chemistry and Homogeneous Catalysis, and Biomolecular Chemistry
2001 Member of the scientific board of the Twelfth European Symposium on Organic Synthesis.
2002 Member of the scientific board of the International Chemistry Olympiad 2002
2002 Member of the European COST network D21 and D24 on asymmetric catalysis.
2005 Member of the board of the Backerfonds (foundation that promotes Organic Chemistry in The Netherlands)
2006 Member of the board of the Netherlands Institute for Catalysis Research (NIOK)
2007 Member of the organizing committee of the 11th international Conference on Circular Dichroism
2007 Member of the German Chemical Society (GDCh)
2008 Member of the board of the Stratingh Institute for Chemistry (University of Groningen)
2008 Associate member of the Zernike Institute of Advanced Materials (University of Groningen)
2008 Member of the Top-Research School NRSC-Catalysis
2008 Member of the International Advisory Board of the European Journal of Organic Chemistry
2010 Chairman of the Dutch Science Foundation Study group Design and Synthesis
2011 Member of the International Advisory Board of the Asian Journal of Organic Chemistry
 2012 Chairman of the board of the Stratingh Institute for Chemistry (University of Groningen)
 2012 Director of Teaching, Chemistry & Chemical Technology (University of Groningen)
 2013 Member of the Advisory board of the HRSMC Summer school, New Vistas in Organic Synthesis
 2013 Associate member of the Groningen Institute of Biology and Biotechnology (University of Groningen)
 2013 Member of the Scientific Advisory Board of the twelfth European Symposium on Organic Chemistry
 2014 Member of the Scientific Advisory Board of the Lorentz Center (International Center for Workshops in the Sciences)
 2016 Director of the Stratingh Institute for Chemistry

Publications

  • Contributions to books: 5
  • Patents: 5
  • papers in international refereed  journals: 230, see publication list,
  • h-index = 54.

Minnaard is scientific advisor of the companies AgileBiotics and KE-Instruments

15 of the main publications of Minnaard as corresponding author since 2012:

1. Wan, I. C., Witte, M. D., Minnaard, A. J. 2017 ‘Site-​selective carbon-​carbon bond formation in unprotected monosaccharides using photoredox catalysis’ Chemical Communications, vol 53, no. 36, pp. 4926-4929.

2. Buter, J.; Heijnen, D.; Vila, C.; Hornillos, V.; Otten, E.; Giannerini, M.; Minnaard, A. J.; Feringa, B. L. Palladium-Catalyzed, tert-Butyllithium-Mediated Dimerization of Aryl Halides and Its Application in the Atropselective Total Synthesis of Mastigophorene A. Angew. Chem. Int. Ed. 2016, 55, 3620-3624.

3. Armenise, N.; Tahiri, N.; Eisink, N.N.H.M.; Denis, M.; Jager, M.; De Vries, J.G.; Witte, M.D.; Minnaard, A.J. Deuteration enhances catalyst lifetime in palladium-catalysed alcohol oxidation Chem. Comm. 2016, 52, 2189-2191.

4. Jäger, M.; Minnaard, A.J. Regioselective modification of unprotected glycosides. Chem. Comm. 2016, 52, 656-664.

5. Geerdink, D.; Minnaard, A. J. Total synthesis of Sulfolipid-1. Chem. Comm. 2014, 50, 2286-2288.

6. Wu, Z.; Harutyunyan, S. R.; Minnaard, A. J. Total Synthesis of (R,R,R)-γ-Tocopherol through Cu-Catalyzed Asymmetric 1,2-Addition. Chem. Eur. J. 201420, 14250-14255.

7. Fodran, P.; Minnaard, A.J. Catalytic synthesis of enantiopure mixed diacylglycerols – synthesis of a major M. tuberculosis phospholipid and platelet activating factor. Org. Biomol. Chem. 2013, 11, 6919-6928.

8. Jaeger, M.; Hartmann, M.; de Vries, J.G.; Minnaard, A.J. Catalytic Regioselective Oxidation of Glycosides. Angew. Chem., Int. Ed2013, 52, 7809-7812.

9. Kortmann, F. A.; Chang, M.-C.; Otten, E.; Couzijn, E. P. A.; Lutz, M.; Minnaard, A. J. Consecutive dynamic resolutions of phosphine oxides. Chem. Science 2014, 5, 1322-1327.

10. Wu, Z.; Harutyunyan, S. R.; Minnaard, A. J. Total Synthesis of (R,R,R)-γ-Tocopherol through Cu-Catalyzed Asymmetric 1,2-Addition. Chem. Eur. J. 2014, 20, 14250-14255.

11. Geerdink, D.; ter Horst, B.; Lepore, M.; Mori, L.; Puzo, G.; Hirsch, A.K.H.; Gilleron, M.; de Libero, G.; Minnaard A.J. Total synthesis, stereochemical elucidation and biological evaluation of Ac2SGL; a 1,3-methyl branched sulfoglycolipid from Mycobacterium tuberculosis. Chem. Sci. 2013, 4, 709-716.

12. Matcha, K.; Madduri, A. V. R.; Roy, S.; Ziegler, S.; Waldmann, H.; Hirsch, A. K. H.; Minnaard, A.J. Total Synthesis of (-)-Doliculide, Structure-Activity Relationship Studies and Its Binding to F-Actin. ChemBioChem 2012, 13, 2537-2548.

13. Barroso, S.; Castelli, R.; Baggelaar, M.P.; Geerdink, D.; ter Horst, B.; Casas-Arce, E.; Overkleeft, H. S.; van der Marel, G. A.; Codee, J. D. C.; Minnaard A. J. Total Synthesis of the Triglycosyl Phenolic Glycolipid PGL-tb1 from Mycobacterium tuberculosis. Angew. Chem., Int. Ed. 2012, 51, 11774-11777.

14. Madduri, A.V. R.; Harutyunyan, S. R.; Minnaard, A. J. Asymmetric Copper-Catalyzed Addition of Grignard Reagents to Aryl Alkyl Ketones. Angew. Chem., Int. Ed. 2012, 51, 3164-3167.

15. Buter, J.; Moezelaar, R.; Minnaard, A. J. Enantioselective palladium catalyzed conjugate additions of ortho-substituted arylboronic acids to β,β-disubstituted cyclic enones: total synthesis of herbertenediol, enokipodin A and enokipodin B. Org. Biomol. Chem. 2014, 12, 5883-5890.